Synthesis, spectroscopic and biological studies of a fluorescent Pt(II) (terpy) based 1,8-naphthalimide conjugate as a DNA targeting agent.
نویسندگان
چکیده
The bi-functional complex [Pt(II)(terpy)(py-naphth)](NO3)2(), incorporating both 2,2':6',2''-terpyridine and 4-N,N'-dimethylamino-1,8-naphthalimide moieties, displays a high binding affinity for DNA as well as displaying cytotoxicity towards and inducing apoptosis in malignant cell lines.
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ورودعنوان ژورنال:
- Chemical communications
دوره 49 76 شماره
صفحات -
تاریخ انتشار 2013